• Association of menopausal characteristics and risk of coronary heart disease: A pan-European case-cohort analysis 

      Dam, Veerle; van der Schouw, Yvonne T.; Onland-Moret, N. Charlotte; Groenwold, Rolf H.H.; Peters, Sanne A.E.; Burgess, Stephen; Wood, Angela M.; Chirlaque, Maria-Dolores; Moons, Karel G.M.; Oliver-Williams, Clare; Schuit, Ewoud; Tikk, Kaja; Weiderpass, Elisabete; Holm, Marianne; Tjønneland, Anne; Kühn, Tilman; Fortner, Renée T.; Trichopoulou, Antonia; Karakatsani, Anna; La Vecchia, Carlo; Ferrari, Pietro; Gunter, Marc; Masala, Giovanna; Sieri, Sabina; Tumino, Rosario; Panico, Salvatore; Boer, Jolanda M.A.; Verschuren, W.M. Monique; Salamanca-Fernández, Elena; Arriola, Larraitz; Moreno-Iribas, Conchi; Engström, Gunnar; Melander, Olle; Nordendahl, Maria; Wennberg, Patrik; Key, Timothy J.; Colorado-Yohar, Sandra; Matullo, Giuseppe; Overvad, Kim; Clavel-Chapelon, Francoise; Boeing, Heiner; Ramõn Quirõs, Jose; di Angelantonio, Emanuele; Langenberg, Claudia; Sweeting, Michael J.; Riboli, Elio; Wareham, Nicholas J.; Danesh, John; Butterworth, Adam (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-02-22)
      <i>Background</i> - Earlier age at menopause has been associated with increased risk of coronary heart disease (CHD), but the shape of association and role of established cardiovascular risk factors remain unclear. Therefore, we examined the associations between menopausal characteristics and CHD risk; the shape of the association between age at menopause and CHD risk; and the extent to which these ...
    • Consumption of meat, fish, dairy products, and eggs and risk of ischemic heart disease: A prospective study of 7198 incident cases among 409 885 participants in the Pan-European EPIC Cohort 

      Key, Timothy J.; Appleby, Paul N.; Bradbury, Kathryn E.; Sweeting, Michael; Wood, Angela; Johansson, Ingegerd; Kühn, Tilman; Steur, Marinka; Weiderpass, Elisabete; Wennberg, Maria; Würtz, Anne Mette Lund; Agudo, Antonio; Andersson, Jonas; Arriola, Larraitz; Boeing, Heiner; Boer, Jolanda M.A.; Bonnet, Fabrice; Boutron-Ruault, Marie-Christine; Cross, Amanda J.; Ericson, Ulrika; Fagherazzi, Guy; Ferrari, Pietro; Gunter, Marc; Huerta, José María; Katzke, Verena; Khaw, Kay-Tee; Krogh, Vittorio; La Vecchia, Carlo; Matullo, Giuseppe; Moreno-Iribas, Conchi; Naska, Androniki; Nilsson, Lena Maria; Olsen, Anja; Overvad, Kim; Palli, Domenico; Panico, Salvatore; Molina-Portillo, Elena; Quirós, J. Ramón; Skeie, Guri; Sluijs, Ivonne; Sonestedt, Emily; Stepien, Magdalena; Tjønneland, Anne; Trichopoulou, Antonia; Tumino, Rosario; Tzoulaki, Ioanna; van der Schouw, Yvonne T.; Verschuren, W.M. Monique; di Angelantonio, Emanuele; Langenberg, Claudia; Forouhi, Nita; Wareham, Nick; Butterworth, Adam; Riboli, Elio; Danesh, John (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-04-22)
      <i>Background</i> - There is uncertainty about the relevance of animal foods to the pathogenesis of ischemic heart disease (IHD). We examined meat, fish, dairy products, and eggs and risk for IHD in the pan-European EPIC cohort (European Prospective Investigation Into Cancer and Nutrition).<P><P> <i>Methods</i> - In this prospective study of 409 885 men and women in 9 European countries, diet ...
    • Dietary amino acids and risk of stroke subtypes: a prospective analysis of 356,000 participants in seven European countries 

      Tong, Tammy Y. N.; Clarke, Robert Michael; Schmidt, Julie A.; Huybrechts, Inge; Noor, Urwah; Forouhi, Nita G.; Imamura, Fumiaki; Travis, Ruth C.; Weiderpass Vainio, Elisabete; Aleksandrova, Krasimira; Dahm, Christina C.; van der Schouw, Yvonne T.; Overvad, Kim; Kyrø, Cecilie; Tjønneland, Anne; Kaaks, Rudolf; Katzke, Verena; Schiborn, Catarina; Schulze, Matthias B.; Mayen-Chacon, Ana-Lucia; Masala, Giovanna; Sieri, Sabina; de Magistris, Maria Santucci; Tumino, Rosario; Sacerdote, Carlotta; Boer, Jolanda M. A.; Verschuren, W. M. Monique; Brustad, Magritt; Nøst, Therese Haugdahl; Crous-Bou, Marta; Petrova, Dafina; Amiano, Pilar; Huerta, José María; Moreno-Iribas, Conchi; Engström, Gunnar; Melander, Olle; Johansson, Kristina; Lindvall, Kristina; Aglago, Elom K.; Heath, Alicia K.; Butterworth, Adam S.; Danesh, John; Key, Timothy J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-07)
      Purpose - Previously reported associations of protein-rich foods with stroke subtypes have prompted interest in the assessment of individual amino acids. We examined the associations of dietary amino acids with risks of ischaemic and haemorrhagic stroke in the EPIC study.<p> <p>Methods - We analysed data from 356,142 participants from seven European countries. Dietary intakes of 19 individual ...
    • Dietary fatty acids, macronutrient substitutions, food sources and incidence of coronary heart disease: Findings from the EPIC-CVD case-cohort study across nine european countries 

      Steur, Marinka; Johnson, Laura; Sharp, Stephen J.; Imamura, Fumiaki; Sluijs, Ivonne; Key, Timothy J.; Wood, Angela M.; Chowdhury, Rajiv; Guevara, Marcela; Jakobsen, Marianne Uhre; Johansson, Ingegerd; Koulman, Albert; Overvad, Kim; Sánchez, Maria-José; van der Schouw, Yvonne T.; Trichopoulou, Antonia; Weiderpass, Elisabete; Wennberg, Maria; Zheng, Ju-Sheng; Boeing, Heiner; Boer, Jolanda M. A.; Boutron-Ruault, Marie-Christine; Ericson, Ulrika; Heath, Alicia K.; Huybrechts, Inge; Imaz, Liher; Kaaks, Rudolf; Krogh, Vittorio; Kühn, Tilman; Kyrø, Cecilie; Masala, Giovanna; Melander, Olle; Moreno-Iribas, Conchi; Panico, Salvatore; Quirós, José R.; Rodríguez-Barranco, Miguel; Sacerdote, Carlotta; Santiuste, Carmen; Skeie, Guri; Tjønneland, Anne; Tumino, Rosario; Monique Verschuren, Verschuren; Zamora-Ros, Raúl; Dahm, Christina C.; Perez-Cornago, Aurora; Schulze, Matthias B.; Tong, Tammy Y.N.; Riboli, Elio; Wareham, Nick; Danesh, John; Butterworth, Adam S.; Forouhi, Nita G. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-07)
      BACKGROUND: There is controversy about associations between total dietary fatty acids, their classes (saturated fatty acids [SFAs], monounsaturated fatty acids, and polyunsaturated fatty acids), and risk of coronary heart disease (CHD). Specifically, the relevance of food sources of SFAs to CHD associations is uncertain.<p> METHODS AND RESULTS: We conducted a case-cohort study involving 10 529 ...
    • Genetically determined reproductive aging and coronary heart disease: a bidirectional two-sample Mendelian Randomization 

      Dam, Veerle; Onland-Moret, N. Charlotte; Burgess, Stephen; Chirlaque, Maria Dolores; Peters, Sanne A.E.; Schuit, Ewoud; Tikk, Kaja; Weiderpass, Elisabete; Oliver-Williams, Clare; Wood, Angela M.; Tjønneland, Anne; Dahm, Christina C; Overvad, Kim; Boutron-Rualt, Marie-Christine; Schulze, Matthias B.; Trichopoulou, Antonia; Ferrari, Pietro; Masala, Giovanna; Krogh, Vittorio; Tumino, Rosario; Matullo, Giuseppe; Panico, Salvatore; Boer, Jolanda M. A.; Verschuren, W.M. Monique; Waaseth, Marit; Pérez, María José Sánchez; Amiano, Pilar; Imaz, Liher; Moreno-Iribas, Conchi; Melander, Olle; Harlid, Sophia; Nordendahl, Maria; Wennberg, Patrik; Key, Timothy J.; Riboli, Elio; Santiuste, Carmen; Kaaks, Rudolf; Katzke, Verena; Langenberg, Claudia; Wareham, Nicholas J.; Schunkert, Heribert; Erdmann, Jeanette; Willenborg, Christina; Hengstenberg, Christian; Kleber, Marcus E.; Delgado, Graciela; März, Winfried; Kanoni, Stavroula; Dedoussis, George; Deloukas, Panos; Nikpay, Majid; McPherson, Ruth; Scholz, Markus; Teren, Andrej; Butterworth, Adam S.; van der Schouw, Yvonne T. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-20)
      Background: Accelerated reproductive aging, in women indicated by early natural menopause, is associated with increased coronary heart disease (CHD) risk in observational studies. Conversely, an adverse CHD risk profile has been suggested to accelerate menopause.<p> <p>Objectives: To study the direction and evidence for causality of the relationship between reproductive aging and (non-)fatal CHD ...
    • Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies 

      Wood, Angela M.; Kaptoge, Stephen; Butterworth, Adam S.; Willeit, Peter; Warnakula, Samantha; Bolton, Thomas; Paige, Ellie; Paul, Dirk S.; Sweeting, Michael; Burgess, Stephen; Bell, Steven; Astle, William; Stevens, David; Koulman, Albert; Selmer, Randi; Verschuren, W.M. Monique; Sato, Shinichi; Njølstad, Inger; Woodward, Mark; Salomaa, Veikko; Nordestgaard, Børge G.; Yeap, Bu B.; Fletcher, Astrid; Melander, Olle; Kuller, Lewis H.; Balkau, Beverley; Marmot, Michael; Koenig, Wolfgang; Casiglia, Edoardo; Cooper, Cyrus; Arndt, Volker; Franco, Oscar H.; Wennberg, Patrik; Gallacher, John; de la Cámara, Agustín Gómez; Völzke, Henry; Dahm, Christina C.; Dale, Caroline E.; Bergmann, Manuela M.; Crespo, Carlos J.; van der Schouw, Yvonne T.; Kaaks, Rudolf; Simons, Leon A.; Lagiou, Pagona; Schoufour, Josje D.; Boer, Jolanda M.A.; Key, Timothy J.; Rodriguez, Beatriz; Moreno-Iribas, Conchi; Davidson, Karina W.; Taylor, James O.; Sacerdote, Carlotta; Wallace, Robert B.; Quiros, J. Ramon; Tumino, Rosario; Blazer, Dan G.; Linneberg, Allan; Daimon, Makoto; Panico, Salvatore; Howard, Barbara; Skeie, Guri; Strandberg, Timo; Weiderpass, Elisabete; Nietert, Paul J.; Psaty, Bruce M.; Kromhout, Daan; Salamanca-Fernández, Elena; Kiechl, Stefan; Krumholz, Harlan M.; Grioni, Sara; Palli, Domenico; Huerta, Jose M.; Price, Jackie; Sundström, Johan; Arriola, Larraitz; Arima, Hisatomi; Travis, Ruth C.; Panagiotakos, Demosthenes B.; Karakatsani, Anna; Trichopoulou, Antonia; Kühn, Tilman; Grobbee, Diederick E.; Barrett-Connor, Elizabeth; van Schoor, Natasja; Boeing, Heiner; Overvad, Kim; Kauhanen, Jussi; Wareham, Nick; Langenberg, Claudia; Forouhi, Nita; Wennberg, Maria; Despres, Jean-Pierre; Cushman, Mary; Cooper, Jackie A.; Rodriguez, Carlos J.; Sakurai, Masaru; Shaw, Jonathan E.; Knuiman, Matthew; Voortman, Trudy; Meisinger, Christa; Tjønneland, Anne; Brenner, Hermann; Palmieri, Luigi; Dallongeville, Jean; Brunner, Eric J.; Assmann, Gerd; Trevisan, Maurizio; Gillum, Richard F.; Ford, Ian; Sattar, Naveed; Lazo, Mariana; Thompson, Simon G.; Ferrari, Pietro; Leon, David A.; Smith, George Davey; Peto, Richard; Jackson, Rod; Banks, Emily; Di Angelantonio, Emanuele; Danesh, John (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-12)
      <p><i>Background - </i>Low-risk limits recommended for alcohol consumption vary substantially across different national guidelines. To define thresholds associated with lowest risk for all-cause mortality and cardiovascular disease, we studied individual-participant data from 599 912 current drinkers without previous cardiovascular disease. <p><i>Methods - </i>We did a combined analysis of ...